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It would appear from our findings that the minimum adequate intake values determined in a VA setting in older people by Tuttle et al [6] may closer to being accurate than those currently accepted as the RDA

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The difference is driven by retatrutide's triple mechanism (GLP-1 + GIP + glucagon) vs Foundayo's single GLP-1 mechanism

Tirzepatide (Mounjaro for type 2 diabetes, Zepbound for weight management) is a dual GIP/GLP-1 receptor agonist that produces significant weight loss through appetite suppression and metabolic effects