While proteins typically provide structure, peptides are usually more focused on signaling
In MDA-MB-231 cells, CuPDTC induces calpain-dependent PARP1 cleavage and apoptosis, and this process is reversed by calpastatin (a calpain inhibitor) (Milacic et al., 2008)
Techniques like PET and twophoton microscopy allow longitudinal monitoring of pathological progression in living animals
Sun F, Kanthasamy A, Anantharam V, Kanthasamy AG (2007) Environmental neurotoxic chemicals-induced ubiquitin proteasome system dysfunction in the pathogenesis and progression of Parkinson's disease
Peptide supporters have asked the FDA to consider the seven peptides under review this week for various medical conditions, including ulcerative colitis, migraines and opioid addiction
Eli Lilly has multiple Phase 3 TRIUMPH trials expected to complete throughout the current year