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Specifically, tenapanorto be marketed as Xphozahis intended for CKD patients on dialysis who have previously shown an inadequate response to phosphate binders or who are otherwise intolerant of such therapies
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However, these side effects typically subside as the body adjusts to the medication
Nature 581 , 434443 (2020)
When NNMT is overactive as it tends to be in fat tissue, and increasingly with age and obesity it siphons off the very raw material your cells need to keep NAD+ topped up
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