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GLP-1 medications also carry an FDA black box warning for risk of thyroid C-cell tumors, and should not be used by patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 (MEN2)

One Reddit user in r/Ozempic put it this way: I dont even like the taste of my wine anymore, yet Im still drinking two glasses a night. Many other threads tell the same story

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Saunders says

When they compared the records of patients prescribed GLP-1 agonists, they found significantly more cases of pancreatitis, gastroparesis and bowel obstruction than in people who used bupropion-naltrexone

We have lab, animal, clinical, and cohort data testifying to their broad effects