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The ENS also expresses GLP-1 receptors 39 , but the local effects of GLP-1 could not be proven because GLP-1RA was ineffective in our studies in Ussing chamber experiments

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Vegetarian and vegan diets, which exclude animal products to varying degrees, can lead to nutrient inadequacies

Patients should be advised to stay well hydrated, eat small frequent meals, and report severe or persistent gastrointestinal symptoms, as these may necessitate dose adjustment or additional management strategies

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In this study, we leverage the recent availability of the AlphaFold3-predicted hTYR structure to investigate the binding modes and inhibitory mechanisms of three natural compounds: arbutin, glutathione, and sea cucumber peptides