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Chronic kidney disease (CKD) and type 2 diabetes mellitus (T2DM) are highly prevalent chronic diseases that represent a significant public health problem and require multidisciplinary management
Vitamin B12 is essential for maintaining healthy blood and nerve cells, as well as for energy metabolism
Melvin George contributed to the study conception and design, data screening, review of data, and manuscript review
Shima Hadidchi
It also supports the composition and activity of the gut microbiome, promoting an increase in beneficial bacteria and the production of short-chain fatty acids
In experimental models, it binds to GHRH receptors located in the anterior pituitary gland, which may stimulate signaling pathways associated with pulsatile growth hormone release
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