Zabezhinski (2002) Inhibitory effect of peptide Epitalon on colon carcinogenesis induced by 1,2-dimethylhydrazine in rats Cancer Letters, Volume 183, Issue 1, 8 September 2002, Pages 1-8
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Mechanisms : Reduces TNF-alpha (key inflammatory marker) Lowers IL-6 and IL-1 (inflammatory cytokines) Modulates immune cell activity Protects tissues from inflammatory damage Applications : Joint pain (arthritis, synovitis) Inflammatory bowel conditions Autoimmune conditions (supportive therapy) General systemic inflammation Protocol : 1-2mg daily injectable, 8-12 weeks Expected results : 40-60% inflammation reduction, improved symptoms, better quality of life
It combines glutathione with Tranexamic Acid, Arbutin, Niacinamide, Kojic Acid, Azelaic Acid, Ferulic Acid, and Encapsulated Retinol
It also has a tyrosine residue to replace the first amino acid at the N-terminus, which researchers consider to help increase the stability of the peptide
Researchers often use 10100 nM final concentration for cell-based assays