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Think of it as a roadblock in your digestive system
Simultaneously, polyamines reshape the immunosuppressive microenvironment, specifically manifested by the recruitment and activation of myeloid-derived suppressor cells and the induction of M2-type tumor-associated macrophage polarization, thus enabling tumors to evade immune surveillance (Figure 3B)
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This means the same dose injected in a damaged site may absorb differently than the same dose in healthy tissue, making your dosage chart unreliable
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