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Standard rapid-release formulas, even if absorbed, create a brief spike in blood levels followed by a rapid crash, whereas sustained-release formulations maintain a therapeutic window that provides round-the-clock cellular protection
Bibcode:1998JAFC...46..206W
Compounds that showed at least 50% inhibition of CMFDA binding to GSTO were selected for doseresponse determinations
By clarifying the relationship between neutrophils and AILI, targeting neutrophils may become a novel promising strategy for treating APAP hepatotoxicity
Arrowsmith JB, Kennedy DL, Kuritsky JN, Faich GA
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