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They have an incretin action, reducing glucose plasmatic levels through the stimulation of insulin secretion by the pancreatic beta-cells and the concomitant inhibition of glucagon secretion by alpha-cells
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Thus, future clinical trials must assess the long-term effect of GLP-1RA treatment
The first 30 infusions are delivered on a weekly basis and the last 10 are delivered during a maintenance phase every two to eight weeks
However, despite improved survival and less cancers with mAb treatment, no significant effect was observed on maximum lifespan ( P = 0.971)
Please remember: All GLP-1 prescriptions require an office visit
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