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Increasing the number of intestinal endocrine L-cells According to the impairment of L-cells development in T2DM, a promising strategy for treating T2DM is to increase the number of L-cells in the intestine, thereby increasing the production of GLP-1
Nanovesicles-mediated drug delivery for oral bioavailability enhancement
These outcomes are largely anecdotal and may stem from the peptides influence on melanocortin receptors, which could affect neurotransmitter activity
Rodents have a much higher density of GLP-1 receptors on thyroid C-cells compared to humans, making them more susceptible to C-cell proliferation
However the anxiety and depressive-like behavior caused by LPS has been demonstrated to decrease after receiving B-immunogalacto-oligosaccharide (222)
Maarouf, O
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