GLP-1 helps control appetite, balance blood sugar, reduce cravings, and support fat loss while protecting lean muscle
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Tirzepatide Tirzepatide introduced dual GIP/GLP-1 receptor activation, delivering greater weight loss than earlier GLP-1 therapies and redefining expectations for pharmacologic obesity management
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There is thus a clear need for a trial over a longer period looking at these areas
It is important to note that a direct, well-established causal link between GLP-1 receptor agonist use and clinically significant B12 deficiency has not been confirmed in the published literature