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Delivery of insulin directly to the CNS is possible through intranasal devices, which, in early trials, has been shown to improve cognition compared to placebo in AD patients [159]

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The metabolic defense mechanisms that had been suppressed by GLP-1 agonism reengaged fully

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Strategies for managing afternoon energy: ensure adequate morning protein to sustain blood sugar, take a brief 10 to 15 minute walk after lunch, get bright light exposure in the early afternoon, and consider whether a small protein snack around 3 PM helps without disrupting evening appetite

Medications can be powerful tools, but they work best when they are built into a personalized medical weight loss plan instead of used as a quick fix