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The MHRA-approved indications for these medications are limited to type 2 diabetes mellitus and, for certain formulations, obesity management in adults with specific BMI thresholds as detailed in their SmPCs
Early after diagnosis, first-line treatment includes sulphonylureas however long term efficacy is not established and insulin requirements vary over time
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Top Magn Reson Imaging
In case of CKD, the use of a GLP-1RA with proven cardiovascular benefit is only recommended in those who have not achieved individualized glycemic targets despite SGLT2i treatment, or in whom SGLT2is are contraindicated or not tolerated [6, 8]
Bacteriostatic water has become the standard in most research settings because it maintains sterility through repeated vial access, preserves peptide integrity without interference, and supports efficient multi-dose protocols
