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The gradual titration is designed to allow the body to adjust to GLP-1 receptor activation and minimize gastrointestinal side effects during the initial treatment period

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GCGR activation stimulates hepatic glucose production between meals, increases lipolysis and fatty acid oxidation in the liver, elevates basal energy expenditure, and promotes thermogenesis

"Give me a single example of courage in your life, or that you've witnessed in someone else's, that did not require uncertainty, risk, or emotional exposure," Brown says