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Its estimated that medication is only responsible for 1.4 to 2 percent of cases

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Both types of pigment derive from the common precursor dopaquinone (ortho-quinone of 3,4-dihydroxyphenylalanine) which is formed via the oxidation of l-tyrosine by the melanogenic enzyme tyrosinase

Available from: 3.Rubino DM, Abrahamsson N, Davies M, Hesse D, Greenway FL, Jensen C, et al

8Allen J, Bradley RD

Effects of phenol compounds, glutathione analogues and a diuretic drug on glutathione S-transferase, glutathione reductase and glutathione peroxidase from canine erythrocytes