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Run the math and you get late 2026 as the absolute floor, with 2027 being the most likely approval year for at least the obesity indication

But here is where it gets practical

9 Smoking cessation may be particularly difficult, as patients with diabetes may view tobacco use as part of a weight-control tool

In early stages of prediabetes or mild type 2 diabetes, significant lifestyle changes-such as losing 5-10% of body weight, adopting a low-carb or Mediterranean diet, and exercising regularly-can sometimes lower A1C enough to delay or avoid medication

I almost quit in week 6

Maternal diet during lactation and breast-feeding practices have synergistic association with child diet at 6 years