GLP-1 and Longevity: Beyond Weight Loss Recent animal studies show GLP-1 agonists may extend lifespan in mice with obesity and metabolic disease (Zhang et al., 2021)
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They note that its active ingredient, semaglutide, is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of natural hormones in the body to stimulate insulin secretion, reduce appetite, and slow down gastric emptying