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For weight management, only semaglutide (Wegovy) and liraglutide (Saxenda) are specifically licensed in the UK, with access typically through specialist weight management services according to NICE criteria

It impairs insulin sensitivity, increases cortisol production, and reduces the secretion of growth hormone, which plays a critical role in fat oxidation and muscle preservation during sleep

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The guidelines were also published in Pediatrics, an AAP journal, which has its own industry relationships

Associations of semaglutide with incident and recurrent CUD diagnosis in patients with type 2 diabetes The study population for the analyses of incident CUD diagnosis in patients with T2D consisted of 587,849 patients with T2D who had no prior recorded diagnosis of CUD

However, the researchers suggest that additional mechanisms may also be involved