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Traditionally, they have been studied in isolation, but a burgeoning body of evidence now positions them as manifestations of a shared systemic age-associated metabolic dysfunction ( 2 Sarcopenia and metabolic mechanism Sarcopenia is a multifactorial syndrome driven by a complex interplay of metabolic dysregulations that create a self-perpetuating cycle of muscle wasting ( This metabolic dysfunction is exacerbated by inflammaging, characterized by elevated pro-inflammatory cytokines such as TNF-, IL-6, and C-reactive protein (CRP) ( Mitochondrial dysfunction is another key pillar of sarcopenia

Managing nausea involves strategies like gradual dose increases (titration), dietary adjustments (smaller meals, bland foods), and natural remedies (ginger, peppermint)

Consistency over 90 continuous days is the minimum before evaluating

The postoperative course was uneventful

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Myoglobinuria, the traditional hallmark of this disease was not present in 21% patients in one study [48]