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Current Opinion in Clinical Nutrition & Metabolic Care, 12(6), 588-595

Specific disruption of gliotoxin biosynthesis, via deletion of gliK , which encodes a -glutamyl cyclotransferase, leads to elevated intracellular antioxidant, ergothioneine (EGT), levels, and confirms crosstalk between the biosynthesis of both sulfur-containing moieties

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While IGF-1 plays a role in muscle repair and satellite cell activation, outcomes depend on nutrition, recovery, hormonal balance, and overall health

It also adds to total toxic exposure which increases inflammation and risk of heart disease