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Digests were speed vac for 1 h, and the pellet was dissolved in Buffer A (5% acetonitrile, 0.1% formic acid) and then cleaned using a C18 silica cartridge and dried using a speed vac
On the other hand, when comparing the individual treatment groups to the control group (T1), specific patterns emerged
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Formulated in a stabilized pre-mixed injection pen for SubQ administration , AOD-9604 ensures high systemic bioavailability and consistent plasma levels in controlled environments
Given their multifaceted involvement in CNS pathology, a reactive form of disease-associated astrocytes has emerged as promising, but technically challenging, targets for therapeutic intervention (Liddelow et al., 2017