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Because the TSPO plays a role in steroidogenesis, it has been considered as a therapeutic target for treatment of anxiety disorders (333)
H 2 O 2 also generated through oxidative processes of MAO and XO that are present in the outer mitochondrial membrane and cytosol respectively
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Int Heart J 65(3):487497 Feridooni T, Hotchkiss A, Remley-Carr S, Saga Y, Pasumarthi KB (2011) Cardiomyocyte specific ablation of p53 is not sufficient to block doxorubicin induced cardiac fibrosis and associated cytoskeletal changes
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Tissue distribution data suggest preferential accumulation in adipose depots, consistent with the mechanism-based selectivity investigators have come to expect
