Common side effects may include nausea, diarrhea, constipation, or mild digestive discomfort, especially when first starting treatment
But animal studies extending up to 6 months show no organ toxicity or adverse histological changes (Sikiric et al., Toxicology and Applied Pharmacology, 2019)
For decades the pharmacology was either ineffective or unsafe sometimes both and so weight was treated as a willpower problem. We finally have molecules that move the right endpoints in the right direction, with a side-effect profile most people who need them can manage
Recording food intake, bowel movements, and any associated symptoms provides valuable information for clinical review
If you experience discomfort when taking B12 on its own, try taking it with healthy, non-greasy foods that wont worsen symptoms like nausea and heartburn
Emily was very helpful and informative