Dec 2014;8(6):688-694
Long-Term Weight Loss & Maintenance with Semaglutide in Obesity (2022 Review of STEP Trials) consolidates findings across multiple STEP trials (1, 3, 4, 8), showing 14.917.4% mean weight loss over 68 weeks, improved cardiometabolic markers, and better quality-of-life outcomes
Other actions of GLP-1 that also contribute to restoring glucose regulation in Type 2 diabetes include inhibition of glucagon secretion, slowing of gastric emptying, suppression of appetite and modest reduction in body weight (37, 48, 84, 118)
10.1111/dom.14048 125
Has anyone run a head-to-head trial of cagrilintide vs tirzepatide
However, treatment options remain limited, therefore the discovery and development of new treatments for ASUDs is critical