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For instance, QDs coated with a polyethylene glycol (PEG) layer have been formulated into stable nanocomplexes capable of crossing the BBB

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In principle, this is not surprising, because models of complex diseases such as brain diseases, as a rule, either involve some of the known mechanisms of the pathogenesis of these diseases, or simply mimic individual symptoms, but never fully reproduce the pathogenesis and symptoms of the disease

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If you experience significant nausea, vomiting, or other gastrointestinal symptoms, your doctor may recommend remaining at your current dose for an additional period before advancing, or may slow the escalation schedule