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A study assessing the acute effect of liraglutide in vagotomized subjects did implicate the vagus nerve in mediating the appetite effect (188), but the sample size in the study was small and subjects had a very low appetite at baseline, making it difficult to draw conclusions

This is a critical concern for anti-aging and long-term metabolic health

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Research into the Protein Leverage Hypothesis (often cited in journals like Obesity Reviews ) suggests that the body will continue to signal hunger and create food noise until its protein requirements are met

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