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But the evidence is mixed, study quality is variable, and benefits in pregnancy or live birth are much harder to prove consistently

Tirzepatide (Zepbound) produces 22.5%, and semaglutide (Wegovy) produces 14.9%

Form Health may recommend GLP-1 treatment for adults with a BMI of 30 or above, or a BMI of 27 when accompanied by a weight-related condition

The mechanism of action involves binding to GLP-1 receptors on pancreatic beta cells, which stimulates glucose-dependent insulin secretion whilst simultaneously suppressing glucagon release

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