In some cases, people might experience dizziness, headache, or an allergic reaction
Who should take B12 injections
If youre exploring peptides because: GLP-1 side effects are limiting, youve plateaued and want a smarter plan, or youre trying to lose fat without sacrificing muscle, then the right next step is a structured metabolic review: whats driving weight, whats driving hunger, whats driving adherence, and which interventions actually address your bottleneck
Overall, compared with 25 mg of methylcobalamin, a 50 mg twice weekly intramuscular injection is more likely to delay functional decline in patients with early-stage ALS with moderate progression rate
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A separate 2024 meta-analysis (Alshammari et al.) confirmed the same conclusion, further strengthening the evidence base