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For the side effect phenotypes, we defined separate casecontrol phenotypes for each side effect recorded in the survey, contrasting those who self-rated their side effects as moderate or severe (cases) to those who self-rated their side effects as mild or non-existent (controls)

Also more complex side effect profile during titration

Treatment Frequency : Space out treatments by 7-10 days to allow the body to process the released fat and minimize potential side effects

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The 15mg dose produced 20.9% average weight loss, translating to approximately 48 lbs for someone starting at 231 lbs