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Once opened, vials remain microbiologically stable for up to 28 days when stored appropriately

It's worth noting that recovery follows a predictable pattern: blood cell production typically begins improving within 3-5 days, haemoglobin rises over 1-2 months, while neurological recovery may take several months

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Concurrent medications (metformin, PPIs, antibiotics) and underlying gastrointestinal conditions may cause diarrhoea coinciding with B12 supplementation

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Less frequently, some people might experience temporary fatigue, dizziness, or nausea