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Its primary area of research is in metabolic conditions, focusing on its potential effects on glucose regulation, appetite, and energy expenditure

If you're a strict vegetarian or vegan, you're at higher risk of B12 deficiency since plant-based foods don't naturally have B12

Functional assessment may require mitochondrial respiration, proton-leak measurements, tissue temperature, oxygen consumption, adrenergic responsiveness, cold challenge, or whole-body energy-expenditure measurements

Because most of what the test measures is inert haptocorrin-bound B12, it is entirely possible to have a normal or even high total B12 while your cells are functionally short

[PMID: 18227641] PubMed record related to this compound for laboratory literature review

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