(2014) Safety and Metabolism of AOD9604, a Novel Nutraceutical Ingredient for Improved Metabolic Health J Endocrinol Metab 4(1-2):114
And now its emerging as a powerful tool in longevity science and functional medicine, thanks to its ability to indirectly boost NAD+ levels by slowing the rate of depletion
Reported adverse effects included mild injection site reactions and transient headaches
Potential therapeutic effects (based on animal and early human data): Enhances tendon, ligament, and muscle repair Promotes angiogenesis (formation of new blood vessels) Reduces inflammation and oxidative stress Protects gut mucosa and may aid in GI disorders (ulcers, leaky gut) May support neurological recovery and joint health Modulates nitric oxide and dopamine/serotonin pathways (possible mood, focus benefits) (Note: Most data are from preclinical studies
When elevated, there was increased fat accumulation, reduced metabolic efficiency, and mitochondrial dysfunction
The compound could theoretically interact with medications affecting NAD+ metabolism, energy pathways, or the enzymes responsible for its clearance from the body