These emerging applications offer researchers opportunities to study senescence contributions to neurodegeneration and develop novel approaches for studying brain aging and neurodegenerative disease mechanisms
( Another, Phase 2 randomized, double-blind, clinical trial that examined the efficacy and safety of CNM-Au8 in subjects having early symptoms of ALS (NCT04098406) and already receiving steady background therapy, such as riluzole was conducted
Another application of DSIP could be the treatment of narcolepsy
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It has been found that the knockout of Mfn2 leads to neurodegeneration due to oxidative stress in the brain [313]
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