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Reinbothe et al
Science 366 , eaax6624 (2019)
Subsequently, 20 mL of pyrogallol was added, and the absorbance was immediately recorded every 30 s for 3 min at 420 nm using a UVvisible Shimadzu spectrophotometer
Bacterial challenges generally induced multiple GSTs, however individual members of the GST family were specifically modified depending upon the virulence of bacterial strains and the outcome of interaction
Indeed, nifurtimox and benznidazole, current drugs administered to treat acute ChD, generate a non-specific oxidative effect over pathogen macromolecules
In addition to neuroimmune regulation, various microbial metabolites affect oxidative stress pathways, with particular indole derivatives and butyrate increasing antioxidant enzyme expression and decreasing reactive oxygen species buildup in neurons
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