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To measure the early IgM response, the same dose of TNP-Ficoll (Biosearch Technologies F-1300-100) was administered i.p., and blood was collected one day previous injection and 3, 5, and 7 days post injection

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Many of the physiological problems that astronauts experience in space, such as motion sickness and otolith dysfunction as well as cardiovascular, bone, and muscle deterioration, are caused by the absence of normal terrestrial gravity (1 g) and the ensuing lack of mechanical stimulation of cells and tissues

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