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In brief, the enhanced cross-cellular transport of Pt drugs is mediated by the uptake via OCTs and efflux via MATE1, respectively (Yang et al., 2021), in which OXA and CP have been found to be substrates of the human OCT family and the human MATE family (Yokoo et al., 2007)

(2025, Olympia) Safety Concerns Compounded GLP1s lack the FDA approval that commercially manufactured drugs undergo, meaning they may not have been subjected to the same rigorous testing for safety and efficacy

Individuals closer to a healthy BMI also tend to lose a higher proportion of fat-free mass (which includes muscle) compared to those with more body fat to lose