RMD Open 8 , e002255 (2022)
Large doses of canthaxanthin may have unpleasant side effects and can cause serious health issues, according to the hives and welts liver damage canthaxanthin retinopathy, a condition where crystals form in the retina of the eye stomach cramps and diarrhea nausea aplastic anemia, where the body stops producing enough new blood cells Some of these side effects may disappear as soon as a person stops taking the pills
The receptor population recovers within 710 days of peptide cessation, which is why cycling protocols (5 days on, 2 days off, or 3 weeks on, 1 week off) prevent tolerance buildup
However, higher doses increase cost without established evidence of proportionally increased benefit
If time is of the essence, keep two teaspoons in the freezer and massage them gently around the eyes
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