Intake of water-soluble dietary fiber, including pectins, gums, fructans and some resistant starches, has been shown to have many similar effects to the goals of GLP-1 therapy , such as: regulating both short and long-term glycemic control improving insulin sensitivity lowering blood cholesterol reducing the risk of cardiovascular disease 31,32 Both soluble and insoluble fibers also modulate microbiome composition and function, improving digestive health and supporting weight management
Sleep and depression are considered to be closely related
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Abbreviations ARB: Angiotensin receptor blocker CKD: Chronic kidney disease CRP: C-reactive protein DKA: Diabetic ketoacidosis DKD: Diabetic kidney disease ERA: Endothelin receptor antagonist ESKD: End-stage kidney disease GIP: Glucose-dependent insulinotropic polypeptide GLP1: Glucagon-like peptide 1 GLP1-RA: Glucagon-like peptide 1 receptor agonist HF: Heart failure hsCRP: High-sensitivity C-reactive protein MACE: Major adverse cardiovascular events MRA: Mineralocorticoid receptor antagonist NO: Nitric oxide RAS: Reninangiotensin system sGC: Soluble guanylate cyclase SGLT2i: Sodiumglucose cotransporter-2 inhibitor(s) UACR: Urine albumin to creatinine ratio References Rossing P, Caramori ML, Chan JCH et al (2022) KDIGO 2022 clinical practice guideline for diabetes management in chronic kidney disease
People with lower levels of L-carnitine, such as vegetarians, vegans, and older adults, can benefit from supplements
These include: Those with a history of cancer: IGF-1 can be involved in the growth of certain types of cancer