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A wave of 2nd generation GLP-1 agonists came to market between 2014-2021, improving clinical outcomes and providing more convenient dosing and administration options
It is administered through small subcutaneous injections
If a medication helps with both the psychiatric symptoms and the maladaptive eating behaviors, thats powerful
A landmark human trial published in Nature Medicine by Depommier and colleagues (2019) showed that pasteurized Akkermansia supplementation improved insulin sensitivity, reduced total cholesterol, and decreased body weight slightly in overweight and obese individuals over a three-month period
Tirzepatide (The Potent Powerhouse) Tirzepatide is a newer-generation medication that acts on both GLP-1 and GIP receptors, another gut hormone
MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism
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