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Dose-by-dose weight loss in Phase 2 (NEJM) Phase 2 NEJM weight loss by dose, 24 and 48 weeks Dose 1 mg 24 weeks -7.2% 48 weeks -8.7% Dose 4 mg 24 weeks -12.9% 48 weeks -17.5% Dose 8 mg 24 weeks -15.7% 48 weeks -22.8% Dose 12 mg 24 weeks -17.5% 48 weeks -24.2% Dose Placebo 24 weeks -1.6% 48 weeks -2.1% Source: Jastreboff et al., NEJM 2023

Conditions in which BPC-157 dosage for dogs by weight might not be prescribed

Newer data around higher maintenance doses has shown potential weight loss results reaching up to 21% over a longer period

One serving of the product 12 g (2 tablespoons) consume 2 times a day during meals

S., Langmead, C.J., Gloriam, D.E., Danev, R., Sexton, P.M., Wootten, D

The substrate-binding domain has a three-layer alpha/beta/alpha structure