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PubChem Compound Summary for 5-Amino-1-methylquinolinium (5-Amino-1MQ)
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2020 safety paper is considered essential reading for any researcher evaluating this compounds translational potential
showed that Se boosted GPX1 expression by inhibiting DNMT2-mediated DNA methylation of the GPX1 promoter from lessening ROS production in advanced glycation end-product (AGE)-induced heart failure [114]
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Interestingly, substituting the amino acids with alanine enhanced the peptides inhibitory ability (Table 1)
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