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Technical Characteristics Active Substance Concentration: 50,000 ppm (5%) Copper Tripeptide-1

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Microglial activation, and interleukin expression specifically, is regulated by Bmal1 expression (Takano et al., 2009), along with a circadian variation in markers involved in oxidation, NADPH oxidase 2 (Nox2), and inflammatory TNF, IL1 and IL-6 in microglia increased during the light or inactive phase in nocturnal mice