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The (2S,3S) configuration specified in the IUPAC name indicates controlled stereochemical orientation
TB-500, as the active fragment of thymosin beta-4, has been widely adopted in preclinical research as a more practical tool for investigating these repair pathways
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579 MaksoudRBalinasCHoldenSCabanasHStainesDMarshall-GradisnikS
Figure 3 below summarizes these processes, highlighting the interplay between bacterial infection, immune mediators (e.g., TNF-, IL-6, transforming growth factor-beta [TGF-], IL-10), and cellular actors (e.g., neutrophils, M1/M2 macrophages, fibroblasts, keratinocytes, endothelial cells) during wound healing [43, 48]
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