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Large population studies have shown that unexplained B12 levels above 813 pg/mL are associated with an increased risk of cancer diagnosis within one year, though the absolute risk for any individual is still relatively low

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Pharmacol Res 158:104844 Kamarajan P, Rajendiran TM, Kinchen J, Bermdez M, Danciu T, Kapila YL (2017) Head and neck squamous cell carcinoma metabolism draws on glutaminolysis, and stemness is specifically regulated by glutaminolysis via aldehyde dehydrogenase