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A 2021 study observed nearly 2,000 adults with excess body weight or obesity who didnt have diabetes

The primary injury results in localized brain damage, while the secondary damage initiates inflammatory responses, followed by the disruption of the blood-brain barrier, infiltration of peripheral blood cells, brain edema, and the release of various immune mediators, including chemotactic factors and interleukins

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Kumari, A., Chetelat, A., Nguyen, C

This helped shift medicine away from viewing organs as isolated structures and toward understanding the body as a connected communication system

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