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HIF-1 is activated due to blockade of its degradation pathway mediated by low oxygen levels, thereby increasing the expression of target genes, including those encoding glycolytic enzymes and glucose transporters, and increasing lactate secretion 67
As such, individual participants may have up to 25 years of longitudinal EMR data, though the actual span varies by individual
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[PMID: 3074366] PubMed record related to this compound for laboratory literature review
doi: 10.1094/Phyto-72-810 3 BensonJ
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