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It is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist

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doi: 10.1007/s11130-024-01192-9 165 WangQSLiMLiXZhangNWHuHYZhangLLet al

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Related Stories Endotrophin may reveal metabolic risks linked to changing body fat Researchers propose new framework to define clinical obesity Oral semaglutide reduces heavy drinking in adults with alcohol use disorder Individuals receiving semaglutide and tirzepatide generally had lower hazards of several recorded neuropsychiatric diagnoses when compared to bariatric surgery recipients

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Evaluation of treatment efficacy should not rely solely on weight reduction but also on endpoints such as fat mass (FM) and lean body mass (LBM)

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The advantages of GLP-1 agonists include substantial clinical trial data supporting their efficacy and safety, FDA approval for weight management in certain populations, proven results with many users losing 15-20% or more of body weight, and effects on appetite that make caloric restriction feel natural

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La historia de los medicamentos basados en GLP-1 tiene un origen fascinante que comenz con el estudio del lagarto venenoso conocido como monstruo de Gila (Heloderma suspectum), nativo del suroeste de Estados Unidos y Mxico

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