It is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist
doi: 10.1007/s11130-024-01192-9 165 WangQSLiMLiXZhangNWHuHYZhangLLet al
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Evaluation of treatment efficacy should not rely solely on weight reduction but also on endpoints such as fat mass (FM) and lean body mass (LBM)
The advantages of GLP-1 agonists include substantial clinical trial data supporting their efficacy and safety, FDA approval for weight management in certain populations, proven results with many users losing 15-20% or more of body weight, and effects on appetite that make caloric restriction feel natural
La historia de los medicamentos basados en GLP-1 tiene un origen fascinante que comenz con el estudio del lagarto venenoso conocido como monstruo de Gila (Heloderma suspectum), nativo del suroeste de Estados Unidos y Mxico