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Specifically, kisspeptin regulates the release of gonadotrophin-releasing hormone (GnRH) from the hypothalamus
-Synuclein aggregates can directly inhibit GCase activity and set up a futile feed-forward loop to increase both -synuclein levels and neurotoxicity (Mazzulli et al., 2011)
Vaish S et al
Cell 130:797810 Linciano P, Cendron L, Gianquinto E, Spyrakis F, Tondi D (2019) Ten years with New Delhi metallo-beta-lactamase-1 (ndm-1): from structural insights to inhibitor design
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