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The acquired data set composed of the peak intensities was generated for a targeted mass inclusion list of metabolites with Fiehnlab BinBase database annotations 37 , database identifier [i.e., InChI key 40 , the compound annotation metadata (i.e., retention index, quantification mass, BinBase identifier, and mass spectrum), and PubChem and KEGG annotations 41,42

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These findings embody EEs systemic potential: by safeguarding mitochondrial and neurotrophic integrity, EE functions as a multi-system pro-resilience modalitynot targeting one lesion but reinforcing defense across different degenerative axes